Sulfuric Acid

Sulfuric Acid

SCHEMBL284773

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nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.82
MEN1 O00255 1/20 0.82
ALDH1A1 P00352 1/20 0.82
KMT2A Q03164 1/20 0.82
CA5A P35218 2/20 0.55
CA5B Q9Y2D0 2/20 0.55
TP53 P04637 1/20 0.39
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36
NT5E P21589 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 2/20 0.35
BLM P54132 1/20 0.35
DUSP5 Q16690 1/20 0.31
DUSP6 Q16828 1/20 0.31
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL10380349 1.00 TSHR (0.82) TSHRMEN1ALDH1A1KMT2ACA5A
Sulfuric Acid SCHEMBL5333935 1.00 TSHR (0.82) TSHRMEN1ALDH1A1KMT2ACA5A
Sulfuric Acid SCHEMBL31150970 1.00 TSHR (0.82) TSHRMEN1ALDH1A1KMT2ACA5A
Sulfuric Acid SCHEMBL391483 1.00 TSHR (0.82) TSHRMEN1ALDH1A1KMT2ACA5A
Sulfuric Acid SCHEMBL8994454 1.00 TSHR (0.82) TSHRMEN1ALDH1A1KMT2ACA5A
Sulfuric Acid SCHEMBL10378601 1.00 TSHR (0.82) TSHRMEN1ALDH1A1KMT2ACA5A
Sulfuric Acid SCHEMBL4959556 1.00 TSHR (0.82) TSHRMEN1ALDH1A1KMT2ACA5A
Sulfuric Acid SCHEMBL10378602 1.00 TSHR (0.82) TSHRMEN1ALDH1A1KMT2ACA5A
Sulfuric Acid SCHEMBL10746243 1.00 TSHR (0.82) TSHRMEN1ALDH1A1KMT2ACA5A
Sulfuric Acid SCHEMBL28368179 0.96 TSHR (0.75) TSHRMEN1ALDH1A1KMT2ACA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11859221-B2 Enzyme variants and polynucleotides encoding the same NOVOZYMES A/S (DK) 2024-01-02 US disclosed
EP-3452497-A1 ALPHA-AMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING THE SAME Novozymes A/S (DK) 2019-03-13 EP disclosed
EP-3440180-A2 DETERGENT COMPOSITIONS AND USES OF THE SAME Novozymes A/S (DK) 2019-02-13 EP disclosed
EP-3397761-A1 ENZYME VARIANTS AND POLYNUCLEOTIDES ENCODING THE SAME Novozymes A/S (DK) 2018-11-07 EP disclosed
WO-2017191160-A1 ALPHA-AMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING THE SAME NOVOZYMES A/S (DK) 2017-11-09 WO disclosed
WO-2017174769-A2 DETERGENT COMPOSITIONS AND USES OF THE SAME NOVOZYMES A/S (DK) 2017-10-12 WO disclosed
WO-2017114891-A1 ENZYME VARIANTS AND POLYNUCLEOTIDES ENCODING THE SAME NOVOZYMES A/S (DK) 2017-07-06 WO disclosed
CN-101932703-B There is the alpha-amylase variants of the characteristic of change DANISCO US INC. (US) 2015-08-05 CN disclosed
CN-101848986-B Alpha-amylase variants with altered properties DANISCO US INC 2014-12-03 CN disclosed
CN-101848985-B Variants of bacillus sp. TS-23 alpha-amylase with altered properties DANISCO US INC 2014-12-03 CN disclosed
US-5856164-A DISHWASHING; CLEANING COMPOUND NOVO NORDISK A/S (DK) 1999-01-05 US disclosed
US-5856451-A CONJUGATING A POLYPEPTIDE WITH A POLYMER NOVO NORDISK A/S (DK) 1999-01-05 US disclosed
US-5827719-A DNA SEQUENCE ISOLATED FOR SACCHAROMYCES CEREVISIAE DSM NOVO NORDISK A/S (DK) 1998-10-27 US disclosed
EP-0851913-A1 NOVEL LIPOLYTIC ENZYMES NOVO NORDISK A/S (DK) 1998-07-08 EP disclosed
US-5741688-A Alkaline glucose oxidase obtained from cladosporium oxysporum NOVO NORDISK A/S (DK) 1998-04-21 US disclosed
WO-1997039116-A1 ENZYME-CONTAINING GRANULES AND PROCESS FOR THE PRODUCTION THEREOF NOVO NORDISK A/S (DK) 1997-10-23 WO disclosed
WO-1997030148-A1 CONJUGATION OF POLYPEPTIDES NOVO NORDISK A/S (DK) 1997-08-21 WO disclosed
WO-1997007202-A1 NOVEL LIPOLYTIC ENZYMES NOVO NORDISK A/S (DK) 1997-02-27 WO disclosed
WO-1997004078-A1 A MODIFIED ENZYME WITH LIPOLYTIC ACTIVITY NOVO NORDISK A/S (DK) 1997-02-06 WO disclosed
WO-1996040791-A1 MODIFICATION OF POLYPEPTIDES NOVO NORDISK A/S (DK) 1996-12-19 WO disclosed