SCHEMBL28477357

SCHEMBL28477357

OB(O)c1cccc2ccc(O)cc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.55
HTR5A P47898 1/20 0.46
CYP1A2 P05177 2/20 0.45
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
ENPP2 Q13822 1/20 0.42
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
TRPV1 Q8NER1 7/20 0.41
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
CDK4 P11802 1/20 0.39
CCND1 P24385 1/20 0.39
PTPN1 P18031 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29957465 0.84 TLR8 (0.46) MCL1CYP1A2ENPP2ESR1ESR2
SCHEMBL4794960 0.84 TLR8 (0.46) MCL1CYP1A2ENPP2ESR1ESR2
SCHEMBL24807944 0.80 CYP2A6 (0.45) CYP1A2ENPP2TRPV1
SCHEMBL3200547 0.80 CYP1A2 (0.59) MCL1CYP1A2MEN1KMT2A
SCHEMBL29951724 0.80 CYP1A2 (0.59) MCL1CYP1A2MEN1KMT2A
SCHEMBL29091226 0.79 CYP1A2 (0.41) CYP1A2ENPP2KDM4EMEN1MAPT
SCHEMBL29957471 0.78 CTDSP1 (0.58) ENPP2KDM4EMEN1MAPTKMT2A
SCHEMBL28704846 0.78 CYP2A6 (0.43) CYP1A2MEN1KMT2ACYP2D6CYP2C9
SCHEMBL6117604 0.78 ALDH1A1 (0.61) CYP1A2MAPT
SCHEMBL16061157 0.78 CYP1A2 (0.43) CYP1A2ENPP2TRPV1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111936506-B Compound and organic light-emitting element comprising same 株式会社LG化学 2023-11-07 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-111936506-A Compound and organic light-emitting element comprising same 株式会社LG化学 2020-11-13 CN disclosed