Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.54 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668094 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL30231092 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL30343292 | 0.98 | ALDH1A1 (0.59) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL29004523 | 0.98 | ALDH1A1 (0.59) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL28514330 | 0.94 | ALDH1A1 (0.60) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL31439757 | 0.94 | ALDH1A1 (0.60) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL31439752 | 0.94 | ALDH1A1 (0.60) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL11455551 | 0.88 | KDM4E (0.63) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL30343301 | 0.88 | KDM4E (0.63) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL30996109 | 0.85 | KDM4E (0.58) | ALDH1A1KDM4EHSD17B10LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920706-B | Method for preparing 3-acyl-quinoxaline-2 (1H) -ketone by ball milling method | 新乡市润宇新材料科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-115385863-A | Synthetic method of 3- (diethoxymethyl) -1-alkyl-2 (1H) -quinoxalinone derivative | 河南师范大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-108033922-B | Preparation method of 3-acyl quinoxalinone derivative | 河南工业大学 | 2020-11-06 | — | — | CN | disclosed |