Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11484366 | 0.79 | MT-CO2 (0.44) | MT-CO2ALOX5SLC18A3CREBBPMEN1 | |
| SCHEMBL11473867 | 0.78 | MT-CO2 (0.43) | MT-CO2ALOX5SLC18A3CREBBPMEN1 | |
| SCHEMBL24820969 | 0.78 | MT-CO2 (0.43) | MT-CO2ALOX5SLC18A3CREBBPMEN1 | |
| SCHEMBL24806685 | 0.78 | MT-CO2 (0.43) | MT-CO2ALOX5SLC18A3CREBBPMEN1 | |
| SCHEMBL14369925 | 0.74 | PSEN1 (0.51) | MT-CO2ALOX5SLC18A3CREBBPMEN1 | |
| SCHEMBL361599 | 0.72 | DDB1 (0.48) | MT-CO2ALOX5SLC18A3KMT2AALOX15 | |
| SCHEMBL11476638 | 0.71 | SLC6A2 (0.40) | MT-CO2ALOX5KMT2A | |
| SCHEMBL415662 | 0.70 | MEN1 (0.65) | MEN1KMT2AALDH1A1MAOAMAOB | |
| SCHEMBL11904658 | 0.70 | MEN1 (0.65) | MEN1KMT2AALDH1A1MAOAMAOB | |
| SCHEMBL20754082 | 0.70 | MEN1 (0.46) | SLC18A3MEN1KMT2AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586284-B | Axial chiral aryl olefin compound and synthesis method thereof | 杭州师范大学 | 2020-11-06 | — | — | CN | disclosed |