Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184035 | 0.87 | HRH4 (0.36) | HRH4 | |
| SCHEMBL5602329 | 0.85 | HRH4 (0.35) | CYP11B2ALDH1A1HRH4 | |
| SCHEMBL5600191 | 0.85 | HRH4 (0.35) | CYP11B2ALDH1A1HRH4 | |
| SCHEMBL5602322 | 0.85 | HRH4 (0.35) | CYP11B2ALDH1A1HRH4 | |
| SCHEMBL5600182 | 0.85 | HRH4 (0.35) | CYP11B2ALDH1A1HRH4 | |
| SCHEMBL5601695 | 0.85 | HRH4 (0.35) | CYP11B2ALDH1A1HRH4 | |
| SCHEMBL5602384 | 0.85 | HRH4 (0.35) | CYP11B2ALDH1A1HRH4 | |
| SCHEMBL4798376 | 0.85 | HRH4 (0.35) | CYP11B2ALDH1A1HRH4 | |
| SCHEMBL5603196 | 0.83 | — | — | |
| SCHEMBL2820732 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109759-B | Carbonyl reductase LsCR mutant, engineering bacterium and application thereof in preparation of chiral alcohol by asymmetric reduction of carbonyl compound | 浙江工业大学 | 2024-05-03 | — | — | CN | disclosed |
| CN-117686599-A | Analysis and detection method for nitrosamine impurities in ticagrelor | 常州制药厂有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-115089590-B | Application of cyclopentyl triazolopyrimidine as pharmaceutical ingredient in hepatitis drugs | 同济大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-111978305-B | Preparation process of ticagrelor intermediate | 南京一心和医药科技有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-111978327-B | Preparation method of ticagrelor | 南京一心和医药科技有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-111978326-A | Production process of ticagrelor competitive product | 南京一心和医药科技有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-111978328-A | Synthesis method of ticagrelor | 南京一心和医药科技有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-111978305-A | Preparation process of ticagrelor intermediate | 南京一心和医药科技有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-111978327-A | Preparation method of ticagrelor | 南京一心和医药科技有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-111358760-A | Ticagrelor tablet pharmaceutical composition and preparation method thereof | 扬子江药业集团广州海瑞药业有限公司 | 2020-07-03 | — | — | CN | disclosed |