⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184035 | 0.95 | HRH4 (0.36) | — | |
| SCHEMBL5602329 | 0.93 | HRH4 (0.35) | — | |
| SCHEMBL5600182 | 0.93 | HRH4 (0.35) | — | |
| SCHEMBL5602322 | 0.93 | HRH4 (0.35) | — | |
| SCHEMBL5600191 | 0.93 | HRH4 (0.35) | — | |
| SCHEMBL5601695 | 0.93 | HRH4 (0.35) | — | |
| SCHEMBL4798376 | 0.93 | HRH4 (0.35) | — | |
| SCHEMBL5602384 | 0.93 | HRH4 (0.35) | — | |
| SCHEMBL2820732 | 0.91 | — | — | |
| Pyrimidine SCHEMBL28478147 | 0.83 | CYP11B2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| EP-3986553-B1 | CYCLOBUTYL CARBOXYLIC ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2026-03-25 | — | — | EP | disclosed |
| US-12466804-B2 | Cyclobutyl carboxylic acids as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-11-11 | — | — | US | disclosed |
| US-20220235027-A1 | CYCLOBUTYL CARBOXYLIC ACIDS AS LPA ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY | 2022-07-28 | — | — | US | disclosed |
| CN-114599641-A | Cyclobutylcarboxylic acids as LPA antagonists | 百时美施贵宝公司 | 2022-06-07 | — | — | CN | disclosed |
| EP-3986553-A1 | CYCLOBUTYL CARBOXYLIC ACIDS AS LPA ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2022-04-27 | — | — | EP | disclosed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |