SCHEMBL28478152

SCHEMBL28478152

C=C(C)C(=O)OCC(C)C(C(C)C)C(C)C

nearest known ligand 0.64

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.64
THRB P10828 1/20 0.41
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.34
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7766598 0.88 TSHR (0.69) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL8966000 0.87 TSHR (0.75) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL23494255 0.84 TSHR (0.64) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL10494078 0.82 TSHR (0.67) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL538796 0.82 TSHR (0.67) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL14528754 0.80 TSHR (0.64) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL23494241 0.80 TSHR (0.64) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL8966053 0.80 TSHR (0.64) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL11751837 0.79 TSHR (0.69) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL24562 0.79 TSHR (1.00) TSHRTHRBALDH1A1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111983745-B Optical film, polarizing plate and liquid crystal display device 柯尼卡美能达株式会社 2022-10-21 CN disclosed
CN-111983744-B Optical film and method for producing optical film 柯尼卡美能达株式会社 2022-06-10 CN disclosed
CN-111983744-A Optical film and method for producing optical film 柯尼卡美能达株式会社 2020-11-24 CN disclosed
CN-111983745-A Optical film, polarizing plate and liquid crystal display device 柯尼卡美能达株式会社 2020-11-24 CN disclosed