Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 14/20 | 0.57 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.57 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22398004 | 1.00 | ERBB2 (0.57) | ERBB2MINK1HMOX1PPARGPPARA | |
| SCHEMBL26316779 | 0.91 | ERBB2 (0.51) | ERBB2MINK1 | |
| SCHEMBL22398234 | 0.88 | ERBB2 (0.56) | ERBB2MINK1 | |
| SCHEMBL22398237 | 0.88 | ERBB2 (0.56) | ERBB2MINK1 | |
| SCHEMBL22397959 | 0.88 | ERBB2 (0.59) | ERBB2MINK1HMOX1 | |
| SCHEMBL28475196 | 0.88 | ERBB2 (0.59) | ERBB2MINK1HMOX1 | |
| SCHEMBL22398026 | 0.87 | ERBB2 (0.60) | ERBB2MINK1HMOX1RXRANR1H2 | |
| SCHEMBL22398024 | 0.87 | ERBB2 (0.60) | ERBB2MINK1HMOX1RXRANR1H2 | |
| SCHEMBL24112000 | 0.87 | ERBB2 (0.59) | ERBB2MINK1 | |
| SCHEMBL28470008 | 0.87 | ERBB2 (0.59) | ERBB2MINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886234-B | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-111886234-A | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2020-11-03 | — | — | CN | disclosed |