Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.86 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiosalicylic Acid SCHEMBL28313023 | 0.93 | MAPT (1.00) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL31208541 | 0.93 | MAPT (1.00) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL629705 | 0.93 | MAPT (1.00) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL50376 | 0.93 | MAPT (1.00) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL28449890 | 0.91 | MAPT (0.95) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL28371699 | 0.91 | MAPT (0.95) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL8219754 | 0.91 | MAPT (0.95) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL27484619 | 0.91 | MAPT (0.95) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL10944700 | 0.91 | MAPT (0.95) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL28096335 | 0.91 | MAPT (0.95) | MAPTHDAC8ALDH1A1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825611-A | 4(1H) -quinovone derivatives and uses thereof | 中央研究院 | 2020-10-27 | — | — | CN | disclosed |