Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30094342 | 0.90 | LMNA (0.45) | PTGDR2LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL30094273 | 0.89 | KDM1A (0.48) | PTGDR2LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28482330 | 0.89 | KDM1A (0.48) | PTGDR2LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29730703 | 0.89 | KDM1A (0.48) | PTGDR2LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29730558 | 0.83 | LMNA (0.45) | PTGDR2LMNASMN1; SMN2BRD4GFER | |
| SCHEMBL29730752 | 0.83 | KDM1A (0.41) | PTGDR2LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29730720 | 0.82 | NAMPT (0.42) | LMNASMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL29730609 | 0.81 | LMNA (0.44) | LMNASMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL21423956 | 0.81 | LMNA (0.57) | PTGDR2LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL18258876 | 0.80 | P2RY1 (0.49) | PTGDR2KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502534-A | BET degradant | 协和麒麟株式会社 | 2022-05-13 | — | — | CN | disclosed |
| CN-111936468-A | Compounds with anti-cancer activity | 协和麒麟株式会社 | 2020-11-13 | — | — | CN | disclosed |