Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 4/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31500557 | 0.71 | P2RX7 (0.47) | P2RX7MAPK1 | |
| SCHEMBL14529972 | 0.69 | P2RX7 (0.55) | P2RX7MAPK1LPLLIPG | |
| Hydrochloric Acid SCHEMBL25367828 | 0.68 | P2RX7 (0.53) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL30965858 | 0.66 | P2RX7 (0.80) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL28374765 | 0.65 | P2RX7 (0.38) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL23553614 | 0.64 | P2RX7 (0.48) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL17394855 | 0.64 | P2RX7 (0.37) | P2RX7MAPK1 | |
| SCHEMBL457989 | 0.62 | P2RX7 (0.55) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL2013150 | 0.61 | P2RX7 (0.46) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL169762 | 0.61 | P2RX7 (1.00) | P2RX7MAPK1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406462-B | Tricyclic DLK inhibitors and uses thereof | 豪夫迈·罗氏有限公司 | 2020-11-10 | — | — | CN | disclosed |