Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 11/20 | 0.65 |
| ▸ | KDM1A | O60341 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | AURKA | O14965 | 2/20 | 0.63 |
| ▸ | KDR | P35968 | 8/20 | 0.62 |
| ▸ | EGFR | P00533 | 6/20 | 0.62 |
| ▸ | FLT4 | P35916 | 2/20 | 0.59 |
| ▸ | CIT | O14578 | 1/20 | 0.59 |
| ▸ | GAK | O14976 | 1/20 | 0.59 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.59 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.59 |
| ▸ | STK17B | O94768 | 1/20 | 0.59 |
| ▸ | STK10 | O94804 | 1/20 | 0.59 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495221 | 0.88 | SRC (0.66) | SRCKDM1AKDM4EAURKAKDR | |
| SCHEMBL13299046 | 0.88 | AURKA (0.67) | SRCKDM1AKDM4EAURKAKDR | |
| SCHEMBL25281864 | 0.88 | SRC (0.66) | SRCKDM1AKDM4EAURKAKDR | |
| SCHEMBL29478521 | 0.87 | EGFR (0.67) | SRCKDM1AKDM4EAURKAKDR | |
| SCHEMBL3530275 | 0.87 | EGFR (0.67) | SRCKDM1AKDM4EAURKAKDR | |
| SCHEMBL4428694 | 0.87 | SRC (0.65) | SRCKDM1AKDM4EAURKAKDR | |
| SCHEMBL2770275 | 0.87 | EGFR (0.67) | SRCKDM1AKDM4EAURKAKDR | |
| SCHEMBL29540227 | 0.87 | SRC (0.65) | SRCKDM1AKDM4EAURKAKDR | |
| SCHEMBL4422710 | 0.87 | SRC (0.65) | SRCKDM1AKDM4EAURKAKDR | |
| Hydrochloric Acid SCHEMBL27988367 | 0.86 | EGFR (0.66) | SRCKDM1AKDM4EAURKAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727284-B | Preparation method of gefitinib | 鲁南制药集团股份有限公司 | 2020-10-27 | — | — | CN | disclosed |