SCHEMBL28481963

SCHEMBL28481963

c1ccc(-c2cc3nc(-c4ccccc4)c(-c4ccccc4)nc3cc2-c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.59
ALDH1A1 P00352 6/20 0.59
L3MBTL1 Q9Y468 6/20 0.59
KMT2A Q03164 3/20 0.59
ATM Q13315 1/20 0.59
TLR9 Q9NR96 1/20 0.59
GAA P10253 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
NPC1 O15118 1/20 0.53
HPGD P15428 1/20 0.53
RAB9A P51151 1/20 0.53
LMNA P02545 5/20 0.52
TDP1 Q9NUW8 3/20 0.52
MEN1 O00255 2/20 0.52
HTT P42858 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
PIK3R1 P27986 1/20 0.49
PIK3CA P42336 1/20 0.49
PDE10A Q9Y233 1/20 0.48
PKM P14618 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18064493 0.89 L3MBTL1 (0.50) KDM4EALDH1A1L3MBTL1KMT2AATM
SCHEMBL10435353 0.87 KDM4E (0.65) KDM4EALDH1A1L3MBTL1KMT2AATM
SCHEMBL13726905 0.87 MAPK14 (0.54) KDM4EALDH1A1L3MBTL1KMT2AATM
SCHEMBL13727298 0.87 MAPK14 (0.54) KDM4EALDH1A1L3MBTL1KMT2AATM
SCHEMBL13727208 0.87 MAPK14 (0.54) KDM4EALDH1A1L3MBTL1KMT2AATM
SCHEMBL13727566 0.87 MAPK14 (0.54) KDM4EALDH1A1L3MBTL1KMT2AATM
SCHEMBL12146790 0.85 PSMB5 (0.49) KDM4EALDH1A1L3MBTL1KMT2AATM
SCHEMBL12146789 0.85 PSMB5 (0.49) KDM4EALDH1A1L3MBTL1KMT2AATM
SCHEMBL12146794 0.85 PSMB5 (0.49) KDM4EALDH1A1L3MBTL1KMT2AATM
SCHEMBL6726086 0.84 PSMB5 (0.48) KDM4EALDH1A1L3MBTL1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111909103-A Novel quinoxaline luminescent material and preparation method and application thereof 广东工业大学 2020-11-10 CN disclosed