Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28480497 | 0.88 | AAK1 (0.62) | AAK1 | |
| SCHEMBL28482007 | 0.82 | AAK1 (0.61) | AAK1 | |
| SCHEMBL21485372 | 0.82 | AAK1 (0.68) | AAK1 | |
| SCHEMBL28480056 | 0.82 | AAK1 (0.58) | AAK1 | |
| SCHEMBL28478444 | 0.82 | AAK1 (0.60) | AAK1 | |
| SCHEMBL28481850 | 0.81 | AAK1 (0.49) | AAK1 | |
| SCHEMBL28487435 | 0.81 | AAK1 (0.59) | AAK1 | |
| SCHEMBL21508528 | 0.81 | AAK1 (1.00) | AAK1 | |
| SCHEMBL21649259 | 0.81 | AAK1 (1.00) | AAK1 | |
| SCHEMBL20447051 | 0.79 | AAK1 (0.84) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142655-A | Biaryl kinase inhibitors | 百时美施贵宝公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-108368084-B | Biaryl kinase inhibitors | 百时美施贵宝公司 | 2020-10-16 | — | — | CN | disclosed |