Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 16/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 15/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28486477 | 0.83 | KDM4E (0.41) | HSP90AB1HSP90AA1HDAC6 | |
| SCHEMBL2911269 | 0.79 | HDAC6 (0.41) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 | |
| SCHEMBL3134817 | 0.79 | HSP90AB1 (0.41) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 | |
| SCHEMBL8709241 | 0.76 | HSP90AB1 (0.43) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 | |
| SCHEMBL8895990 | 0.74 | HSP90AB1 (0.39) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 | |
| SCHEMBL2912383 | 0.74 | HDAC6 (0.45) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 | |
| SCHEMBL6004137 | 0.73 | HSP90AB1 (0.41) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 | |
| SCHEMBL6002747 | 0.72 | HSP90AB1 (0.42) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 | |
| SCHEMBL6884460 | 0.71 | HSP90AB1 (0.55) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 | |
| SCHEMBL2913721 | 0.71 | HSP90AB1 (0.42) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997429-B | Method for preparing Beciclovir | 广州粤美医药科技有限公司 | 2020-10-30 | — | — | CN | disclosed |