Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2793231 | 0.90 | GAA (0.52) | HTTGAAKMT2AMAPK1TSHR | |
| SCHEMBL2788879 | 0.83 | KMT2A (0.59) | GAAKMT2AMAPK1TSHRNPSR1 | |
| SCHEMBL2789721 | 0.82 | MAPK1 (0.72) | HTTGAAKMT2AMAPK1MMP3 | |
| Potassium Ion SCHEMBL2790164 | 0.81 | KMT2A (0.54) | GAAKMT2AMAPK1TSHRNPSR1 | |
| SCHEMBL5731223 | 0.79 | TRPV1 (0.57) | HTTGAAKMT2ANPC1RAB9A | |
| SCHEMBL2842399 | 0.79 | MAPT (0.58) | HTTGAAKMT2AMAPK1NPSR1 | |
| SCHEMBL2791913 | 0.79 | PTPN1 (0.69) | MAPK1NPC1RAB9ASMN1; SMN2SENP7 | |
| SCHEMBL30754208 | 0.76 | DYRK1A (0.71) | GAAKMT2AMAPK1TSHRNPSR1 | |
| SCHEMBL11714671 | 0.76 | MAPT (0.60) | GAAKMT2AMAPK1TSHRNPSR1 | |
| SCHEMBL3446775 | 0.76 | GAA (0.49) | HTTGAAKMT2AMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012481-B2 | Benzoarylureido compounds, and composition for prevention or treatment of neurodegenerative brain disease containing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-04-21 | — | — | US | disclosed |
| US-9012481-B2 | Benzoarylureido compounds, and composition for prevention or treatment of neurodegenerative brain disease containing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-04-21 | — | — | US | disclosed |
| US-20110319456-A1 | BENZOARYLUREIDO COMPOUNDS, AND COMPOSITION FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE BRAIN DISEASE CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-12-29 | — | — | US | disclosed |
| US-20110319456-A1 | BENZOARYLUREIDO COMPOUNDS, AND COMPOSITION FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE BRAIN DISEASE CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-12-29 | — | — | US | disclosed |
| WO-2010077068-A2 | BENZOARYLUREIDO COMPOUNDS, AND COMPOSITION FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE BRAIN DISEASE CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2010-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319456-A1 | BENZOARYLUREIDO COMPOUNDS, AND COMPOSITION FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE BRAIN DISEASE CONTAINING THE SAME | HTT, PSEN1, PYGB | HTT 1/4885GAA 17/4885KMT2A 3011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.