Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 8/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 8/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 8/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 8/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | POLA1 | P09884 | 1/20 | 0.37 |
| ▸ | POLG | P54098 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30451824 | 0.90 | PI4KA (0.43) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL21518153 | 0.86 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL21518150 | 0.86 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL29641197 | 0.86 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL21590119 | 0.76 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL2449991 | 0.73 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL30451773 | 0.72 | PI4KA (0.42) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL28484184 | 0.70 | PI4KA (0.42) | PI4KAPI4K2BPI4K2API4KBADORA1 | |
| SCHEMBL21518151 | 0.69 | PI4KA (0.45) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL28607691 | 0.68 | ADORA2A (0.51) | PI4KAPI4K2BPI4K2API4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111989335-A | Phosphonamide ester compounds and salts and related crystal forms, preparation methods and uses thereof | 四川科伦博泰生物医药股份有限公司 | 2020-11-24 | — | — | CN | claimed |