Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 5/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 5/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 5/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.34 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21518151 | 0.81 | PI4KA (0.45) | PI4KAPI4K2BPI4K2API4KBSMN1; SMN2 | |
| SCHEMBL28484184 | 0.81 | PI4KA (0.42) | PI4KAPI4K2BPI4K2API4KBSMN1; SMN2 | |
| SCHEMBL2449991 | 0.75 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBSMN1; SMN2 | |
| SCHEMBL30451824 | 0.74 | PI4KA (0.43) | PI4KAPI4K2BPI4K2API4KBSMN1; SMN2 | |
| SCHEMBL29641197 | 0.73 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBSMN1; SMN2 | |
| SCHEMBL21518153 | 0.73 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBSMN1; SMN2 | |
| SCHEMBL21518150 | 0.73 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBSMN1; SMN2 | |
| SCHEMBL28484182 | 0.72 | PI4KA (0.44) | PI4KAPI4K2BPI4K2API4KBSMN1; SMN2 | |
| SCHEMBL15669233 | 0.67 | CYP3A4 (0.51) | CYP3A4SLC22A6 | |
| SCHEMBL15669173 | 0.67 | CYP3A4 (0.51) | CYP3A4SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111989335-B | Phosphonamide ester compounds and salts thereof and related crystalline forms, methods of preparation and uses | 四川科伦博泰生物医药股份有限公司 | 2023-06-13 | — | — | CN | disclosed |