Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.67 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.67 |
| ▸ | ADA | P00813 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.61 |
| ▸ | PNP | P00491 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | PDE2A | O00408 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | NT5E | P21589 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3437025 | 1.00 | ADORA2A (1.00) | ADORA2AADORA3ADORA1ADORA2BADA | |
| SCHEMBL30262576 | 1.00 | ADORA2A (1.00) | ADORA2AADORA3ADORA1ADORA2BADA | |
| SCHEMBL16480951 | 0.89 | ADORA2A (0.80) | ADORA2AADORA3ADORA1ADORA2BADA | |
| SCHEMBL10169502 | 0.89 | ADORA2A (0.80) | ADORA2AADORA3ADORA1ADORA2BADA | |
| SCHEMBL15908433 | 0.89 | ADORA2A (0.80) | ADORA2AADORA3ADORA1ADORA2BADA | |
| SCHEMBL873738 | 0.89 | ADORA2A (0.80) | ADORA2AADORA3ADORA1ADORA2BADA | |
| SCHEMBL14589609 | 0.89 | ADORA2A (0.80) | ADORA2AADORA3ADORA1ADORA2BADA | |
| SCHEMBL474849 | 0.89 | ADORA2A (0.80) | ADORA2AADORA3ADORA1ADORA2BADA | |
| SCHEMBL10137892 | 0.89 | ADORA2A (0.80) | ADORA2AADORA3ADORA1ADORA2BADA | |
| SCHEMBL29815502 | 0.88 | ADORA2A (0.79) | ADORA2AADORA3ADORA1ADORA2BADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848711-A | 2' -chloronucleoside analogs for HCV infection | 埃迪尼克斯医药有限责任公司 | 2020-10-30 | — | — | CN | disclosed |