Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.80 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.61 |
| ▸ | PNP | P00491 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.60 |
| ▸ | PDE2A | O00408 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.54 |
| ▸ | ADA | P00813 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16480837 | 0.90 | ADORA2A (0.66) | ADORA2APDE4DPDE3APNPLMNA | |
| SCHEMBL28484259 | 0.89 | ADORA2A (1.00) | ADORA2APDE4DPDE3APNPLMNA | |
| SCHEMBL30262576 | 0.89 | ADORA2A (1.00) | ADORA2APDE4DPDE3APNPLMNA | |
| SCHEMBL3437025 | 0.89 | ADORA2A (1.00) | ADORA2APDE4DPDE3APNPLMNA | |
| SCHEMBL17615336 | 0.89 | ADORA2A (0.64) | ADORA2APDE4DPDE3APNPLMNA | |
| Ammonia Solution, Strong SCHEMBL19974416 | 0.88 | ADORA2A (0.79) | ADORA2APDE4DPDE3APNPLMNA | |
| SCHEMBL19949236 | 0.88 | ADORA2A (0.79) | ADORA2APDE4DPDE3APNPLMNA | |
| SCHEMBL30262554 | 0.88 | ADORA2A (0.79) | ADORA2APDE4DPDE3APNPLMNA | |
| SCHEMBL29815502 | 0.88 | ADORA2A (0.79) | ADORA2APDE4DPDE3APNPLMNA | |
| SCHEMBL29135436 | 0.85 | ADORA2A (0.77) | ADORA2APDE4DPDE3APNPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160083413-A1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC | 2016-03-24 | — | — | US | disclosed |
| US-20160083413-A1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC | 2016-03-24 | — | — | US | disclosed |
| WO-2014058801-A1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS, INC. (US) | 2014-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083413-A1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | SLC28A2, SLC28A1, SLC29A2 | ADORA2A 300/4885PDE4D 1132/4885PDE3A 1190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.