Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28496249 | 0.78 | ESR1 (0.55) | KCNH2MAPT | |
| SCHEMBL4813125 | 0.78 | KIF11 (0.59) | KIF11CNR1NPBWR1DGAT1KCNH2 | |
| SCHEMBL28486502 | 0.78 | KIF11 (0.51) | KIF11CNR1CDK4CCND1MAPT | |
| SCHEMBL28490064 | 0.74 | KIF11 (0.46) | KIF11CNR1 | |
| SCHEMBL4126997 | 0.72 | KIF11 (1.00) | KIF11CDK4CCND1 | |
| SCHEMBL2289172 | 0.71 | KIF11 (0.61) | KIF11NPBWR1 | |
| SCHEMBL17548341 | 0.70 | CNR1 (0.72) | KIF11CNR1 | |
| SCHEMBL17548345 | 0.70 | CNR1 (0.72) | KIF11CNR1 | |
| SCHEMBL17548507 | 0.70 | CNR1 (0.72) | KIF11CNR1 | |
| SCHEMBL4811581 | 0.70 | KIF11 (0.55) | KIF11CNR1NPBWR1DGAT1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848488-B | Method for synthesizing 3-selenoindole derivative | 温州医科大学 | 2022-12-27 | — | — | CN | disclosed |
| CN-111848488-A | Method for synthesizing 3-selenoindole derivative | 温州医科大学 | 2020-10-30 | — | — | CN | disclosed |