SCHEMBL28485282

SCHEMBL28485282

O=C(OCC(O)O)c1ccc(C(=O)OCC(O)O)cc1.[LiH].[LiH]

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.59
MAPT P10636 1/20 0.50
ADRB2 P07550 13/20 0.49
ADRB1 P08588 13/20 0.49
ADRB3 P13945 13/20 0.49
SLC1A5 Q15758 1/20 0.47
PTPN1 P18031 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
ESR1 P03372 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
ESR2 Q92731 1/20 0.45
CA14 Q9ULX7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL351317 0.98 ALDH1A1 (0.61) ALDH1A1MAPTADRB2ADRB1ADRB3
SCHEMBL29162948 0.92 MAPT (0.62) ALDH1A1MAPTADRB2ADRB1ADRB3
SCHEMBL351318 0.90 MAPT (0.64) ALDH1A1MAPTADRB2ADRB1ADRB3
SCHEMBL13217500 0.87 ALDH1A1 (0.78) ALDH1A1MAPTADRB2ADRB1ADRB3
Lithium Ion SCHEMBL29266499 0.86 ALDH1A1 (0.50) ALDH1A1MAPTADRB2ADRB1ADRB3
SCHEMBL28198371 0.86 ALDH1A1 (0.55) ALDH1A1MAPTADRB2ADRB1ADRB3
Benzoic Acid SCHEMBL10978494 0.85 ALDH1A1 (0.68) ALDH1A1MAPTADRB2ADRB1ADRB3
Phosphonic Acid SCHEMBL11767971 0.83 MAPT (0.57) ALDH1A1MAPTADRB2ADRB1ADRB3
SCHEMBL4762261 0.81 ALDH1A1 (0.58) ALDH1A1ADRB2ADRB1ADRB3PTPN1
SCHEMBL441479 0.80 MAPT (0.58) ALDH1A1MAPTADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111918898-A Copolyesters derived from aliphatic diols, aromatic dicarboxylic acids, and poly (alkylene oxides), and films made therefrom 美国杜邦泰津胶片合伙人有限公司 2020-11-10 CN disclosed