Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21176803 | 0.74 | MEN1 (0.48) | MEN1HTTKMT2ASRCATM | |
| SCHEMBL2854023 | 0.71 | HTT (0.56) | MEN1HTTKMT2ASRCCA2 | |
| SCHEMBL28672425 | 0.71 | MEN1 (0.45) | MEN1HTTKMT2ASRCATM | |
| SCHEMBL27552822 | 0.67 | MEN1 (0.41) | MEN1HTTKMT2ASRCCA2 | |
| Aniline SCHEMBL9347211 | 0.67 | TSHR (0.41) | MEN1HTTKMT2ASRCATM | |
| SCHEMBL2855667 | 0.67 | MEN1 (0.45) | MEN1HTTKMT2ASRCL3MBTL1 | |
| SCHEMBL3065169 | 0.66 | MEN1 (0.54) | MEN1HTTKMT2ASRCCA2 | |
| Pyrophosphoric Acid SCHEMBL31236964 | 0.66 | SRC (0.46) | MEN1HTTKMT2ASRCATM | |
| SCHEMBL29054212 | 0.66 | PTPN1 (0.41) | MEN1HTTKMT2ASRCCA2 | |
| SCHEMBL1297782 | 0.66 | MEN1 (0.44) | MEN1HTTKMT2ASRCCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111770921-A | Quinoxalinone compounds, compositions, methods and kits for improving efficiency of genome editing | 沃泰克斯药物股份有限公司 | 2020-10-13 | — | — | CN | disclosed |