Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21176803 | 0.78 | MEN1 (0.48) | MEN1HTTKMT2ASRCCA2 | |
| SCHEMBL29120368 | 0.78 | SRC (0.47) | MEN1HTTKMT2ASRCCA2 | |
| SCHEMBL2854023 | 0.75 | HTT (0.56) | MEN1HTTKMT2ASRCCA2 | |
| SCHEMBL3065169 | 0.75 | MEN1 (0.54) | MEN1HTTKMT2ASRCCA2 | |
| Methane SCHEMBL10783749 | 0.73 | MEN1 (0.52) | MEN1HTTKMT2ASRCCA2 | |
| SCHEMBL2855667 | 0.71 | MEN1 (0.45) | MEN1HTTKMT2ASRCALDH1A1 | |
| Aniline SCHEMBL9347211 | 0.71 | TSHR (0.41) | MEN1HTTKMT2ASRCCA2 | |
| SCHEMBL28485352 | 0.71 | MEN1 (0.41) | MEN1HTTKMT2ASRCCA2 | |
| SCHEMBL2309806 | 0.70 | MEN1 (0.48) | MEN1HTTKMT2ASRCCA2 | |
| SCHEMBL8530739 | 0.70 | MEN1 (0.48) | MEN1HTTKMT2ASRCCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110913871-B | Generation of mammalian T cell activation inducible synthetic promoters (SYN+PRO) to improve T cell therapy | 西雅图儿童医院（DBA西雅图儿童研究所） | 2024-02-23 | — | — | CN | disclosed |
| CN-110381998-B | anti-LAIR 1 antibodies and uses thereof | 德克萨斯大学体系董事会 | 2023-08-29 | — | — | CN | disclosed |
| CN-109311966-B | Trispecific and/or trivalent binding proteins for use in the prevention or treatment of HIV infection | 赛诺菲 | 2023-03-10 | — | — | CN | disclosed |
| CN-107106611-B | Compositions and methods for improving the efficacy of adoptive cellular immunotherapy | 弗雷德哈钦森癌症研究中心 | 2021-11-23 | — | — | CN | disclosed |