Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 3/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22810499 | 0.92 | — | — | |
| Hydrogen Sulfide SCHEMBL28853138 | 0.90 | PNMT (0.50) | PNMTDPP4LOXL2TAAR1CYP2A6 | |
| SCHEMBL29405036 | 0.74 | PNMT (0.63) | PNMTDPP4LOXL2TAAR1CYP2A6 | |
| SCHEMBL15247 | 0.74 | PNMT (0.63) | PNMTDPP4LOXL2TAAR1CYP2A6 | |
| SCHEMBL21296567 | 0.73 | HSPA5 (0.46) | PNMTDPP4TAAR1 | |
| SCHEMBL16775680 | 0.72 | TAAR1 (0.58) | LOXL2TAAR1CYP2A6 | |
| Benzene SCHEMBL734438 | 0.72 | DPP4 (0.62) | PNMTDPP4LOXL2TAAR1CYP2A6 | |
| Hydrochloric Acid SCHEMBL2522138 | 0.72 | PNMT (0.60) | PNMTDPP4LOXL2TAAR1CYP2A6 | |
| Hydrochloric Acid SCHEMBL31276815 | 0.72 | PNMT (0.60) | PNMTDPP4LOXL2TAAR1CYP2A6 | |
| Water SCHEMBL6142580 | 0.72 | PNMT (0.60) | PNMTDPP4LOXL2TAAR1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111777637-B | Axial chiral oxindole-derived styrene phosphine oxide catalyst and preparation method and application thereof | 江苏师范大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-111777637-A | Axial chiral oxindole-derived styrene phosphine oxide catalyst and preparation method and application thereof | 江苏师范大学 | 2020-10-16 | — | — | CN | disclosed |