Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CHRND | Q07001 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28482434 | 0.83 | MAPT (0.41) | MAPTRAB9ANPC1POLBS100A4 | |
| SCHEMBL28479107 | 0.82 | POLB (0.39) | MAPTRAB9ANPC1POLBS100A4 | |
| SCHEMBL12927900 | 0.80 | POLB (0.46) | POLBHPGDCYP2A6KDM4EALDH1A1 | |
| SCHEMBL940923 | 0.79 | POLB (0.44) | MAPTRAB9ANPC1POLBS100A4 | |
| SCHEMBL28167101 | 0.79 | POLB (0.44) | POLBS100A4HPGDKDM4EALDH1A1 | |
| SCHEMBL6536414 | 0.77 | MAPT (0.52) | MAPTRAB9ANPC1S100A4CHRNA1 | |
| SCHEMBL4402923 | 0.73 | POLB (0.71) | POLBHPGDPKMALDH1A1KMT2A | |
| SCHEMBL30341829 | 0.73 | POLB (0.71) | POLBHPGDPKMALDH1A1KMT2A | |
| SCHEMBL6307676 | 0.72 | POLB (0.54) | MAPTRAB9ANPC1POLBS100A4 | |
| SCHEMBL28751074 | 0.72 | POLB (0.69) | POLBHPGDPKMALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995513-B | Preparation method of 9-hydroxymethyl-fluorenic acid | 天津键凯科技有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-111995513-A | Preparation method of 9-hydroxymethyl-fluorenic acid | 天津键凯科技有限公司 | 2020-11-27 | — | — | CN | claimed |
| CN-111995513-B | Preparation method of 9-hydroxymethyl-fluorenic acid | 天津键凯科技有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-111995513-B | Preparation method of 9-hydroxymethyl-fluorenic acid | 天津键凯科技有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-111995513-A | Preparation method of 9-hydroxymethyl-fluorenic acid | 天津键凯科技有限公司 | 2020-11-27 | — | — | CN | disclosed |
| CN-111995513-A | Preparation method of 9-hydroxymethyl-fluorenic acid | 天津键凯科技有限公司 | 2020-11-27 | — | — | CN | disclosed |