Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | S100A4 | P26447 | 1/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | CHRND | Q07001 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10965346 | 0.91 | HTR7 (0.62) | MAPTRAB9ANPC1HTR7HTR2B | |
| SCHEMBL15180320 | 0.85 | CHRNA1 (0.51) | MAPTRAB9ANPC1S100A4CHRNA1 | |
| SCHEMBL13563804 | 0.85 | CHRNA1 (0.51) | MAPTRAB9ANPC1S100A4CHRNA1 | |
| SCHEMBL19412996 | 0.83 | HTR7 (0.50) | MAPTRAB9ANPC1HTR7HTR2B | |
| SCHEMBL28485704 | 0.77 | MAPT (0.46) | MAPTRAB9ANPC1S100A4CHRNA1 | |
| SCHEMBL28653494 | 0.77 | MAPT (0.42) | MAPTRAB9ANPC1HTR7HTR2B | |
| SCHEMBL7825562 | 0.76 | HTR7 (0.62) | HTR7HTR2BALDH1A1KMT2ALMNA | |
| SCHEMBL30571871 | 0.76 | HTR7 (0.62) | HTR7HTR2BALDH1A1KMT2ALMNA | |
| SCHEMBL8033807 | 0.75 | S100A4 (0.73) | MAPTRAB9ANPC1S100A4HSD17B1 | |
| SCHEMBL23254178 | 0.74 | CYP2A6 (0.50) | MAPTRAB9ANPC1S100A4CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824709-B2 | A LIQUID CRYSTAL COMPOUND OR LIQUID CRYSTAL POLYMERS, CONTAINING ACRYLATE OR METHACRYLATE FLUORENE GROUP; LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20030203128-A1 | Fluorene derivatives and their polymers | JNC PETROCHEMICAL CORPORATION (JP) | 2003-10-30 | — | — | US | disclosed |