Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | TOP1 | P11387 | 2/20 | 0.52 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.51 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28267570 | 0.93 | MEN1 (0.54) | KMT2AMAPTMEN1KDM4EKIF11 | |
| SCHEMBL1259604 | 0.85 | KIF11 (0.56) | KMT2AMAPTMEN1KIF11TRPV3 | |
| SCHEMBL4898700 | 0.84 | SRD5A2 (0.54) | KMT2AMEN1KDM4ENPC1RAB9A | |
| SCHEMBL4895565 | 0.84 | SRD5A2 (0.54) | KMT2AMEN1KDM4ENPC1RAB9A | |
| SCHEMBL9487625 | 0.84 | GRM5 (0.64) | KMT2AMAPTMEN1KDM4EKIF11 | |
| SCHEMBL21003801 | 0.84 | KMT2A (0.61) | KMT2AMAPTMEN1KDM4EL3MBTL1 | |
| SCHEMBL29730468 | 0.84 | KMT2A (0.61) | KMT2AMAPTMEN1KDM4EL3MBTL1 | |
| SCHEMBL18732403 | 0.84 | KMT2A (0.61) | KMT2AMAPTMEN1KDM4EL3MBTL1 | |
| SCHEMBL18731741 | 0.84 | KMT2A (0.61) | KMT2AMAPTMEN1KDM4EL3MBTL1 | |
| Nitrobenzene SCHEMBL2743390 | 0.84 | NPC1 (0.48) | KMT2AMAPTMEN1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110117258-B | Preparation method of 2,4, 6-triaryl substituted pyrimidine compound | 台州学院 | 2020-11-03 | — | — | CN | disclosed |