SCHEMBL28486206

SCHEMBL28486206

CCCC(=O)CC(C)(Br)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 4/20 0.39
HDAC1 Q13547 4/20 0.39
HDAC2 Q92769 4/20 0.39
HDAC8 Q9BY41 4/20 0.39
FFAR3 O14843 3/20 0.39
CES2 O00748 2/20 0.35
CES1 P23141 2/20 0.35
TSHR P16473 3/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
HIF1A Q16665 1/20 0.34
PLA2G4A P47712 1/20 0.32
ALDH1A1 P00352 2/20 0.31
HMGCR P04035 1/20 0.31
CHRM1 P11229 1/20 0.31
TBXA2R P21731 1/20 0.31
ADRA1A P35348 1/20 0.31
IAPP P10997 2/20 0.31
KDM4C Q9H3R0 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7696407 0.77 HDAC3 (0.42) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL28875311 0.74 CES2 (0.43) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL14830770 0.74 TSHR (0.55) FFAR3TSHRCYP2D6CYP2C19HIF1A
SCHEMBL269663 0.74 CES2 (0.43) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL23824840 0.72 CES2 (0.41) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL140406 0.72
SCHEMBL31109129 0.71 HDAC3 (0.40) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL1732575 0.71
SCHEMBL287909 0.71
SCHEMBL1732520 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112011002-A Method for controlled radical polymerization and apparatus for controlled radical polymerization 立邦工业涂料(上海)有限公司 2020-12-01 CN disclosed