Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.60 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | PAM | P19021 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | GNPAT | O15228 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328715 | 1.00 | TACR1 (0.60) | TACR1CTSSCTSKPAMATM | |
| SCHEMBL9493909 | 0.86 | TACR1 (0.61) | TACR1CTSSCTSKPAMATM | |
| SCHEMBL9493914 | 0.86 | TACR1 (0.61) | TACR1CTSSCTSKPAMATM | |
| SCHEMBL6716240 | 0.86 | CTSL (0.53) | TACR1CTSSATMCYP2C9CYP2C19 | |
| SCHEMBL6589100 | 0.86 | CTSL (0.53) | TACR1CTSSATMCYP2C9CYP2C19 | |
| SCHEMBL6372883 | 0.85 | TACR1 (0.56) | TACR1CTSSCTSKPAMATM | |
| SCHEMBL6588838 | 0.85 | TACR1 (0.60) | TACR1CTSSCTSKCTRB1ALDH1A1 | |
| SCHEMBL1884230 | 0.84 | ATM (0.68) | TACR1CTSSCTSKPAMATM | |
| SCHEMBL28943620 | 0.84 | TACR1 (0.66) | TACR1CTSSCTSKPAMATM | |
| SCHEMBL1879654 | 0.84 | ATM (0.68) | TACR1CTSSCTSKPAMATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999323-B2 | Composition that can be cured by polymerisation for the production of biodegradable, biocompatible, cross-linkable polymers on the basis of polyvinyl alcohol | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2015-04-07 | — | — | US | disclosed |
| EP-2428235-B1 | Use of compounds hardened by means of polymerisation for producing biodegradable, biocompatible, networked polymers | UNIV WIEN TECH (AT) | 2014-06-04 | — | — | EP | disclosed |
| US-8357524-B2 | Chemically modified mutant serine hydrolases show improved catalytic activity and chiral selectivity | DANISCO US INC. (US) | 2013-01-22 | — | — | US | disclosed |
| US-20120295329-A1 | CHEMICALLY MODIFIED MUTANT SERINE HYDROLASES SHOW IMPROVED CATALYTIC ACTIVITY AND CHIRAL SELECTIVITY | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2012-11-22 | — | — | US | disclosed |
| US-20120156721-A1 | CHEMICALLY MODIFIED MUTANT SERINE HYDROLASES SHOW IMPROVED CATALYTIC ACTIVITY AND CHIRAL SELECTIVITY | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2012-06-21 | — | — | US | disclosed |
| US-8148128-B2 | Chemically modified mutant serine hydrolases show improved catalytic activity and chiral selectivity | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2012-04-03 | — | — | US | disclosed |
| EP-2428235-A2 | Use of compounds hardened by means of polymerisation for producing biodegradable, biocompatible, networked polymers | Technische Universität Wien (AT) | 2012-03-14 | — | — | EP | disclosed |
| US-20100303804-A1 | COMPOSITION THAT CAN BE CURED BY POLYMERISATION FOR THE PRODUCTION OF BIODEGRADABLE, BIOCOMPATIBLE, CROSS-LINKABLE POLYMERS ON THE BASIS OF POLYVINYL ALCOHOL | TECHNISCHE UNIVERSITAT WIEN (AT) | 2010-12-02 | — | — | US | disclosed |
| EP-2219697-A2 | COMPOSITION THAT CAN BE CURED BY POLYMERISATION FOR THE PRODUCTION OF BIODEGRADABLE, BIOCOMPATIBLE, CROSS-LINKABLE POLYMERS ON THE BASIS OF POLYVINYL ALCOHOL | Technische Universität Wien (AT) | 2010-08-25 | — | — | EP | disclosed |
| EP-1129180-B1 | CHEMICALLY MODIFIED MUTANT SERINE HYDROLASES | UNIV TORONTO (CA) | 2009-06-10 | — | — | EP | disclosed |
| WO-2009065162-A2 | COMPOSITION THAT CAN BE CURED BY POLYMERISATION FOR THE PRODUCTION OF BIODEGRADABLE, BIOCOMPATIBLE, CROSS-LINKABLE POLYMERS ON THE BASIS OF POLYVINYL ALCOHOL | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2009-05-28 | — | — | WO | disclosed |
| US-20090075329-A1 | CHEMICALLY MODIFIED MUTANT SERINE HYDROLASES SHOW IMPROVED CATALYTIC ACTIVITY AND CHIRAL SELECTIVITY | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2009-03-19 | — | — | US | disclosed |
| EP-1604030-B1 | ENZYMATIC PROCESS FOR STEREO-SELECTIVE PREPARATION OF CHEMICAL COMPOUNDS IN HYDROFLUOROCARBON SOLVENTS | INEOS FLUOR HOLDINGS LTD (GB) | 2007-06-20 | — | — | EP | disclosed |
| US-20050282248-A1 | Chemically modified mutant serine hydrolases show improved catalytic activity and chiral selectivity | JONES JOHN B | 2005-12-22 | — | — | US | disclosed |
| US-20040208883-A1 | Method for preparing ester linked peptide-carbohydrate conjugates | ISIS INNOVATION LIMITED (GB) | 2004-10-21 | — | — | US | disclosed |
| EP-1414988-A1 | METHOD FOR PREPARING ESTER LINKED PEPTIDE-CARBOHYDRATE CONJUGATES | ISIS INNOVATION LIMITED (GB) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003014371-A1 | METHOD FOR PREPARING ESTER LINKED PEPTIDE-CARBOHYDRATE CONJUGATES | ISIS INNOVATION LIMITED (GB) | 2003-02-20 | — | — | WO | disclosed |
| EP-1129180-A2 | CHEMICALLY MODIFIED MUTANT SERINE HYDROLASES | GENENCOR INTERNATIONAL, INC. (US) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000028007-A2 | CHEMICALLY MODIFIED MUTANT SERINE HYDROLASES | GENENCOR INTERNATIONAL, INC. (US) | 2000-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100303804-A1 | COMPOSITION THAT CAN BE CURED BY POLYMERISATION FOR THE PRODUCTION OF BIODEGRADABLE, BIOCOMPATIBLE, CROSS-LINKABLE POLYMERS ON THE BASIS OF POLYVINYL ALCOHOL | SCO2, CBR1, CBR3 | TACR1 3570/4885CTSS 4822/4885CTSK 4863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.