Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC5 | O15392 | 1/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17548779 | 0.80 | NPC1 (0.53) | BIRC5PDGFRBPDGFRACYP2A6KDM4E | |
| SCHEMBL26560229 | 0.79 | ESR2 (0.54) | BIRC5PIK3CDPIK3CACYP11B1CYP11B2 | |
| SCHEMBL22008743 | 0.79 | NPC1 (0.53) | BIRC5PIK3CDPIK3CACYP11B1CYP11B2 | |
| SCHEMBL26560198 | 0.75 | PDGFRB (0.50) | BIRC5PIK3CDPIK3CACYP11B1CYP11B2 | |
| SCHEMBL26549330 | 0.75 | PDGFRB (0.54) | BIRC5PIK3CDPIK3CACYP11B1CYP11B2 | |
| SCHEMBL26560216 | 0.75 | PDGFRB (0.55) | BIRC5PIK3CDPIK3CAPDGFRBPDGFRA | |
| SCHEMBL26557991 | 0.75 | PDGFRB (0.50) | BIRC5PIK3CDPIK3CACYP11B1CYP11B2 | |
| SCHEMBL26549030 | 0.75 | PDGFRB (0.54) | BIRC5PIK3CDPIK3CACYP11B1CYP11B2 | |
| SCHEMBL19467303 | 0.75 | BIRC5 (0.66) | BIRC5PIK3CDPIK3CACYP11B1CYP11B2 | |
| SCHEMBL17899315 | 0.74 | CYP11B1 (0.53) | BIRC5PIK3CDPIK3CACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106554352-B | Polycyclic aromatic hydrocarbon derivative containing naphthyridine group and application thereof | 北京鼎材科技有限公司 | 2020-12-08 | — | — | CN | disclosed |