Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14184261 | 0.83 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL28486604 | 0.80 | BIRC5 (0.55) | SMN1; SMN2BIRC5PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL29470857 | 0.78 | DYRK1A (0.52) | SMN1; SMN2BIRC5PDGFRBPDGFRAKDR | |
| SCHEMBL934055 | 0.78 | DYRK1A (0.52) | SMN1; SMN2BIRC5PDGFRBPDGFRAKDR | |
| SCHEMBL5303005 | 0.76 | CYP2A6 (0.51) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL17548800 | 0.76 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL5197973 | 0.76 | BIRC5 (0.63) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL28492581 | 0.74 | CA12 (0.48) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL27114779 | 0.73 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL22909971 | 0.72 | RAB9A (0.70) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106554352-B | Polycyclic aromatic hydrocarbon derivative containing naphthyridine group and application thereof | 北京鼎材科技有限公司 | 2020-12-08 | — | — | CN | disclosed |
| US-20170256719-A1 | COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME | DUK SAN NEOLUX CO., LTD (KR) | 2017-09-07 | — | — | US | disclosed |
| US-20170256719-A1 | COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME | DUK SAN NEOLUX CO., LTD (KR) | 2017-09-07 | — | — | US | disclosed |
| CN-106554352-A | A kind of condensed-nuclei aromatics derivant containing naphthyridines group and its application | 北京鼎材科技有限公司 | 2017-04-05 | — | — | CN | disclosed |
| WO-2016032150-A2 | COMPOUND FOR ORGANIC ELECTRICAL ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME | 덕산네오룩스 주식회사 | 2016-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170256719-A1 | COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME | ORAI2, VDAC2, PIEZO1 | NPC1 2710/4885RAB9A 3355/4885SMN1; SMN2 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.