Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.79 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.72 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.72 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | F3 | P13726 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25497554 | 1.00 | SMN1; SMN2 (0.79) | SMN1; SMN2TAS1R3TAS1R1HDAC3HDAC1 | |
| SCHEMBL28486682 | 1.00 | SMN1; SMN2 (0.79) | SMN1; SMN2TAS1R3TAS1R1HDAC3HDAC1 | |
| SCHEMBL1557352 | 0.88 | SMN1; SMN2 (1.00) | SMN1; SMN2TAS1R3TAS1R1HDAC3HDAC1 | |
| SCHEMBL1557439 | 0.88 | SMN1; SMN2 (1.00) | SMN1; SMN2TAS1R3TAS1R1HDAC3HDAC1 | |
| SCHEMBL28483599 | 0.88 | SMN1; SMN2 (1.00) | SMN1; SMN2TAS1R3TAS1R1HDAC3HDAC1 | |
| SCHEMBL1558855 | 0.88 | SMN1; SMN2 (1.00) | SMN1; SMN2TAS1R3TAS1R1HDAC3HDAC1 | |
| SCHEMBL1557437 | 0.88 | SMN1; SMN2 (1.00) | SMN1; SMN2TAS1R3TAS1R1HDAC3HDAC1 | |
| SCHEMBL1557350 | 0.88 | SMN1; SMN2 (1.00) | SMN1; SMN2TAS1R3TAS1R1HDAC3HDAC1 | |
| SCHEMBL28479291 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2TAS1R3TAS1R1THRBTP53 | |
| SCHEMBL28479289 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2TAS1R3TAS1R1THRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111807983-A | Cinnamic acid derivative and preparation method thereof | 五邑大学 | 2020-10-23 | — | — | CN | claimed |
| CN-111807983-B | Cinnamic acid derivative and preparation method thereof | 五邑大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-111807983-A | Cinnamic acid derivative and preparation method thereof | 五邑大学 | 2020-10-23 | — | — | CN | disclosed |