Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NOS3 | P29474 | 8/20 | 0.55 |
| ▸ | NOS1 | P29475 | 8/20 | 0.55 |
| ▸ | NOS2 | P35228 | 8/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28479291 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2NOS3NOS1NOS2TAS1R3 | |
| SCHEMBL28486683 | 0.87 | SMN1; SMN2 (0.79) | SMN1; SMN2TAS1R3TAS1R1MAPTTP53 | |
| SCHEMBL28489858 | 0.87 | NOS2 (0.70) | SMN1; SMN2NOS3NOS1NOS2TAS1R3 | |
| SCHEMBL28486682 | 0.87 | SMN1; SMN2 (0.79) | SMN1; SMN2TAS1R3TAS1R1MAPTTP53 | |
| SCHEMBL28902465 | 0.87 | NOS2 (0.70) | SMN1; SMN2NOS3NOS1NOS2TAS1R3 | |
| SCHEMBL25497554 | 0.87 | SMN1; SMN2 (0.79) | SMN1; SMN2TAS1R3TAS1R1MAPTTP53 | |
| SCHEMBL28483776 | 0.84 | SMN1; SMN2 (0.71) | SMN1; SMN2TAS1R3TAS1R1MAPTTP53 | |
| SCHEMBL28483777 | 0.84 | SMN1; SMN2 (0.71) | SMN1; SMN2TAS1R3TAS1R1MAPTTP53 | |
| SCHEMBL28481413 | 0.83 | NOS3 (0.72) | SMN1; SMN2NOS3NOS1NOS2TAS1R3 | |
| SCHEMBL28481411 | 0.83 | NOS3 (0.72) | SMN1; SMN2NOS3NOS1NOS2TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111807983-A | Cinnamic acid derivative and preparation method thereof | 五邑大学 | 2020-10-23 | — | — | CN | claimed |
| CN-111807983-B | Cinnamic acid derivative and preparation method thereof | 五邑大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-111807983-A | Cinnamic acid derivative and preparation method thereof | 五邑大学 | 2020-10-23 | — | — | CN | disclosed |