SCHEMBL28486759

SCHEMBL28486759

O=C1Oc2cc(O)cc(O)c2CC1c1ccc(O)cc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.49
PTGS2 P35354 3/20 0.49
CYP19A1 P11511 1/20 0.49
TYR P14679 1/20 0.49
RECQL P46063 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
MAPT P10636 3/20 0.42
THRB P10828 2/20 0.42
CYP3A4 P08684 2/20 0.42
SYNJ2 O15056 1/20 0.42
USP2 O75604 1/20 0.41
ALDH1A1 P00352 2/20 0.41
BACE1 P56817 4/20 0.40
KDM4E B2RXH2 2/20 0.40
GAA P10253 2/20 0.40
PKM P14618 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3493652 0.84 ESR1 (0.55) PTGS1PTGS2CYP19A1RECQLTDP1
SCHEMBL28259872 0.80 ALDH1A1 (0.47) CYP19A1TYRRECQLTDP1MEN1
SCHEMBL17963720 0.80 KDM4E (0.56) PTGS1PTGS2CYP19A1RECQLTDP1
SCHEMBL27882637 0.79 KMT2A (0.48) CYP19A1RECQLTDP1MEN1KMT2A
SCHEMBL572086 0.78 KMT2A (0.41) PTGS1PTGS2CYP19A1RECQLESR1
SCHEMBL18740869 0.77 ALDH1A1 (0.48) CYP19A1RECQLTDP1MEN1KMT2A
SCHEMBL9993959 0.76 ESR1 (0.39) PTGS1CYP19A1RECQLESR1ESR2
SCHEMBL27685813 0.72 ALDH1A1 (0.44) PTGS1PTGS2CYP19A1TYRESR1
SCHEMBL3960495 0.70 ESR2 (0.53) PTGS1PTGS2CYP19A1RECQLTDP1
SCHEMBL15263378 0.70 PTGS1 (0.72) PTGS1PTGS2RECQLTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114887000-A Application of lemongrass medicine 云南农业大学 2022-08-12 CN disclosed
CN-104971086-B Use of Rabbit tail grass for promoting osteogenesis or providing neuroprotection 台北医学大学 2020-12-08 CN disclosed
CN-102613201-B Isoflavanone compound for protecting underwater structure surface and application thereof UNIV YUNNAN NATIONALITIES 2013-10-16 CN disclosed
CN-102613201-A Isoflavanone compound for protecting underwater structure surface and application thereof UNIV YUNNAN NATIONALITIES 2012-08-01 CN disclosed