Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29411875 | 1.00 | L3MBTL1 (0.49) | L3MBTL1MAPTTP53BRD4SMN1; SMN2 | |
| SCHEMBL29412097 | 0.92 | L3MBTL1 (0.50) | L3MBTL1MAPTTP53BRD4ACSS2 | |
| SCHEMBL29412148 | 0.88 | MAPT (0.53) | L3MBTL1MAPTTP53BRD4SMN1; SMN2 | |
| SCHEMBL9122314 | 0.87 | JAK2 (0.54) | MAPTTP53BRD4SMN1; SMN2ACSS2 | |
| SCHEMBL28480003 | 0.83 | BRD4 (0.57) | L3MBTL1MAPTTP53BRD4SMN1; SMN2 | |
| SCHEMBL29411941 | 0.81 | BRD4 (0.52) | L3MBTL1MAPTTP53BRD4SMN1; SMN2 | |
| SCHEMBL29412041 | 0.81 | KDM4E (0.56) | L3MBTL1MAPTTP53BRD4SMN1; SMN2 | |
| SCHEMBL29411955 | 0.80 | TP53 (0.54) | L3MBTL1MAPTTP53BRD4SMN1; SMN2 | |
| SCHEMBL29411994 | 0.79 | TP53 (0.58) | L3MBTL1MAPTTP53BRD4SMN1; SMN2 | |
| SCHEMBL29412011 | 0.79 | BRD4 (0.50) | L3MBTL1MAPTTP53BRD4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978301-B | Benzimidazole compound with endothelial lipase inhibition effect and application thereof | 盐城师范学院 | 2022-08-02 | — | — | CN | disclosed |
| CN-111978301-A | Benzimidazole compound with endothelial lipase inhibition effect and application thereof | 盐城师范学院 | 2020-11-24 | — | — | CN | disclosed |