Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28479454 | 1.00 | CA2 (0.39) | CA2CA1CA12CA14CA7 | |
| SCHEMBL28479453 | 1.00 | CA2 (0.39) | CA2CA1CA12CA14CA7 | |
| SCHEMBL276235 | 0.80 | TSHR (0.32) | CA2CA1CA14CA7 | |
| SCHEMBL13104268 | 0.76 | CA12 (0.36) | CA2CA1CA12CA14CA7 | |
| SCHEMBL16453575 | 0.73 | — | — | |
| SCHEMBL14000040 | 0.73 | — | — | |
| SCHEMBL13104573 | 0.72 | CA12 (0.33) | CA2CA1CA12CA14CA7 | |
| SCHEMBL13104571 | 0.70 | CA12 (0.35) | CA2CA1CA12CA14CA7 | |
| SCHEMBL13104353 | 0.69 | CA12 (0.32) | CA2CA1CA12CA14CA7 | |
| SCHEMBL276258 | 0.69 | CA2 (0.50) | CA2CA1CA12CA14CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207441-B | Protein kinase inhibitors | 上海复尚慧创医药研究有限公司 | 2020-11-24 | — | — | CN | disclosed |