Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826944 | 0.82 | CYP2A6 (0.42) | DYRK1ACYP2A6CYP3A4TSHRALDH1A1 | |
| SCHEMBL31158396 | 0.79 | DYRK1A (0.42) | DYRK1ACYP2A6ALDH1A1MAPTBLM | |
| SCHEMBL20562829 | 0.79 | CYP2A6 (0.37) | DYRK1ACYP2A6ALDH1A1KDM4EMAPT | |
| SCHEMBL12121771 | 0.75 | CYP2A6 (0.37) | DYRK1ACYP2A6ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8427836 | 0.75 | CYP2A6 (0.37) | DYRK1ACYP2A6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL5213461 | 0.75 | PKM (0.43) | DYRK1ACYP2A6CYP3A4TSHRMAPK1 | |
| SCHEMBL14607168 | 0.75 | CYP2A6 (0.37) | DYRK1ACYP2A6KDM4ECA12CA2 | |
| SCHEMBL21931029 | 0.75 | DYRK1A (0.42) | DYRK1ACYP2A6ALDH1A1CA12CA2 | |
| SCHEMBL17970824 | 0.74 | CYP2A6 (0.39) | DYRK1ACYP2A6KDM4ECA12CA2 | |
| SCHEMBL10045628 | 0.74 | CYP2A6 (0.39) | DYRK1ACYP2A6KDM4ECA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025087274-A1 | AZABICYCLO DERIVATIVE AND PREPARATION METHOD THEREFOR, AND USE | 浙江海正药业股份有限公司 | 2025-05-01 | — | — | WO | disclosed |
| CN-109721536-B | Phenyl-substituted fused tricyclic compounds and application thereof | 广东东阳光药业有限公司 | 2020-11-24 | — | — | CN | disclosed |