Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 15/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.40 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | EPN1 | Q9Y6I3 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28488180 | 0.85 | MAPK1 (0.50) | HCAR2DAOMEN1KMT2A | |
| SCHEMBL28111052 | 0.74 | HCAR2 (0.45) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL5317023 | 0.72 | HCAR2 (0.58) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL2360520 | 0.68 | HCAR2 (0.52) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL15467909 | 0.68 | HCAR2 (0.56) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL2662871 | 0.66 | CA12 (0.51) | BTKMEN1KMT2A | |
| SCHEMBL28860793 | 0.66 | HCAR2 (0.53) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL1675620 | 0.66 | HCAR2 (0.34) | HCAR2 | |
| SCHEMBL1748982 | 0.66 | P4HTM (0.50) | ASPH | |
| SCHEMBL19207696 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279808-A | Cystic fibrosis transmembrane transduction modulator modulators | 弗特克斯药品有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-112250627-A | Cystic fibrosis transmembrane transduction modulator modulators | 弗特克斯药品有限公司 | 2021-01-22 | — | — | CN | disclosed |
| CN-107690281-B | Cystic fibrosis transmembrane transduction modulator modulators | 弗特克斯药品有限公司 | 2020-11-17 | — | — | CN | disclosed |