Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 15/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.40 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | EPN1 | Q9Y6I3 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068051 | 0.86 | KMT2A (0.38) | L3MBTL1 | |
| SCHEMBL17224847 | 0.83 | MAPK1 (0.51) | HCAR2L3MBTL1 | |
| SCHEMBL15467909 | 0.78 | HCAR2 (0.56) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL28015264 | 0.74 | L3MBTL1 (0.49) | HCAR2L3MBTL1HCAR3ASPH | |
| SCHEMBL28488240 | 0.74 | HCAR2 (0.43) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL16445300 | 0.74 | HCAR2 (0.60) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL219145 | 0.73 | ALDH1A1 (0.44) | L3MBTL1 | |
| SCHEMBL5317023 | 0.72 | HCAR2 (0.58) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL2360520 | 0.72 | HCAR2 (0.52) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL15350209 | 0.70 | CNR2 (0.42) | HCAR2DAOL3MBTL1ASPH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106255688-B | Morpholine-pyridine derivate | 豪夫迈·罗氏有限公司 | 2019-11-08 | — | — | CN | disclosed |
| CN-106255688-A | Morpholine pyridine derivate | 豪夫迈·罗氏有限公司 | 2016-12-21 | — | — | CN | disclosed |