Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | DRD1 | P21728 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28497871 | 0.99 | GAA (0.52) | GAATSHRTP53HTTTBXA2R | |
| SCHEMBL28403562 | 0.93 | TBXA2R (0.58) | GAATSHRTP53HTTTBXA2R | |
| SCHEMBL6732477 | 0.93 | TBXA2R (0.58) | GAATSHRTP53HTTTBXA2R | |
| SCHEMBL28488906 | 0.89 | GAA (0.48) | GAATSHRTP53HTTTBXA2R | |
| SCHEMBL28356025 | 0.85 | CYP2C9 (0.50) | GAATSHRTP53HTTTBXA2R | |
| SCHEMBL29259269 | 0.82 | GAA (0.48) | GAATSHRTP53HTTTBXA2R | |
| SCHEMBL11130109 | 0.82 | TBXA2R (0.42) | GAATSHRTP53HTTTBXA2R | |
| SCHEMBL14987090 | 0.81 | TSHR (0.74) | GAATSHRTP53HTTTBXA2R | |
| SCHEMBL8199258 | 0.79 | TSHR (0.73) | GAATSHRTP53HTTTBXA2R | |
| SCHEMBL19687545 | 0.79 | TBXA2R (0.66) | GAATSHRTP53HTTTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112010801-A | Preparation method of amlodipine base | 山东汇海医药化工有限公司 | 2020-12-01 | — | — | CN | claimed |
| CN-112010801-A | Preparation method of amlodipine base | 山东汇海医药化工有限公司 | 2020-12-01 | — | — | CN | disclosed |