Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.66 |
| ▸ | DRD1 | P21728 | 2/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.66 |
| ▸ | DRD3 | P35462 | 2/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.66 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.66 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.66 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.66 |
| ▸ | DRD2 | P14416 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459829 | 0.86 | TBXA2R (0.60) | TBXA2RADRA1ASLC6A3HTR1AADRA2A | |
| SCHEMBL6732477 | 0.84 | TBXA2R (0.58) | TBXA2RADRA1ASLC6A3HTR1AADRA2A | |
| SCHEMBL28403562 | 0.84 | TBXA2R (0.58) | TBXA2RADRA1ASLC6A3HTR1AADRA2A | |
| SCHEMBL3377507 | 0.84 | CYP3A4 (0.61) | TBXA2RADRA1ASLC6A3HTR1AADRA2A | |
| SCHEMBL9761425 | 0.84 | TBXA2R (0.59) | TBXA2RADRA1ASLC6A3HTR1AADRA2A | |
| SCHEMBL28342101 | 0.84 | TBXA2R (0.60) | TBXA2RADRA1ASLC6A3HTR1AADRA2A | |
| SCHEMBL30516331 | 0.83 | CYP3A4 (0.49) | TBXA2RADRA1ASLC6A3HTR1AADRA2A | |
| SCHEMBL30516334 | 0.83 | TBXA2R (0.56) | TBXA2RADRA1ASLC6A3HTR1AADRA2A | |
| SCHEMBL22105882 | 0.83 | ADORA3 (0.50) | TBXA2RADRA1ASLC6A3HTR1AADRA2A | |
| SCHEMBL25377373 | 0.82 | TBXA2R (0.90) | TBXA2RADRA1ASLC6A3HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814527-B2 | BILAYER TABLET COMPRISING TELMISARTAN AND AMLODIPINE | BOEHRINGER INGELHEIM INT (DE) | 2020-11-18 | — | — | EP | disclosed |
| US-20200316029-A1 | FIXED DOSE COMBINATION OF TELMISARTAN, HYDROCHLOROTHIAZIDE AND AMLODIPINE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-10-08 | — | — | US | disclosed |
| WO-2017207375-A1 | FIXED DOSE COMBINATION OF TELMISARTAN, HYDROCHLOROTHIAZIDE AND AMLODIPINE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200316029-A1 | FIXED DOSE COMBINATION OF TELMISARTAN, HYDROCHLOROTHIAZIDE AND AMLODIPINE | ACE, AGT, REN | TBXA2R 1229/4885ADRA1A 1987/4885SLC6A3 2702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.