Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 known ✓ | P08588 | 1/20 | 0.36 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1D known ✓ | P25100 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL49513 | 1.00 | TSHR (0.56) | TSHRCYP3A4CPB2BLMLMNA | |
| Cadaverine Tartrate SCHEMBL25240399 | 0.97 | TSHR (0.53) | TSHRCYP3A4CPB2BLMLMNA | |
| Cadaverine Tartrate SCHEMBL786877 | 0.85 | TSHR (0.67) | TSHRBLMLMNAMAPTTDP1 | |
| Cadaverine Tartrate SCHEMBL342524 | 0.85 | TSHR (0.67) | TSHRBLMLMNAMAPTTDP1 | |
| Lactic Acid SCHEMBL14484983 | 0.81 | TP53 (0.58) | TSHRCYP3A4CPB2BLMLMNA | |
| Cadaverine Tartrate SCHEMBL1834853 | 0.80 | TSHR (0.59) | TSHRBLMLMNAMAPTTDP1 | |
| Cadaverine Tartrate SCHEMBL1833811 | 0.80 | TSHR (0.59) | TSHRBLMLMNAMAPTTDP1 | |
| Tartaric Acid SCHEMBL31538119 | 0.80 | TSHR (0.59) | TSHRBLMLMNAMAPTTDP1 | |
| Cadaverine Tartrate SCHEMBL49514 | 0.79 | CYP3A4 (0.40) | TSHRCYP3A4CPB2BLMLMNA | |
| Cysteamine SCHEMBL5502656 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112020348-A | Novel salts of cysteamine for preparing highly inhalable particles | 利康大帝化学医药工业股份有限公司 | 2020-12-01 | — | — | CN | disclosed |