Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.60 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
| ▸ | PPARA | Q07869 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722245 | 1.00 | NR4A1 (0.60) | NR4A1NR4A2NR4A3PPARGPPARA | |
| SCHEMBL2848849 | 1.00 | NR4A1 (0.60) | NR4A1NR4A2NR4A3PPARGPPARA | |
| SCHEMBL10776066 | 0.85 | KMT2A (0.61) | NR4A1NR4A2NR4A3PPARGPPARA | |
| SCHEMBL10776069 | 0.85 | KMT2A (0.61) | NR4A1NR4A2NR4A3PPARGPPARA | |
| SCHEMBL10999770 | 0.85 | NR4A1 (0.62) | NR4A1NR4A2NR4A3PPARGPPARA | |
| SCHEMBL7761599 | 0.85 | NR4A1 (0.62) | NR4A1NR4A2NR4A3PPARGPPARA | |
| SCHEMBL10603321 | 0.84 | LTA4H (0.62) | NR4A1NR4A2NR4A3LMNAMAOB | |
| SCHEMBL7444074 | 0.84 | LTA4H (0.62) | NR4A1NR4A2NR4A3LMNAMAOB | |
| SCHEMBL11490483 | 0.83 | NR4A1 (0.60) | NR4A1NR4A2NR4A3PPARGPPARA | |
| SCHEMBL2873996 | 0.83 | NR4A1 (0.60) | NR4A1NR4A2NR4A3PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54070231-A | — | — | None | — | — | JP | disclosed |
| EP-1633340-B1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | WELLSTAT THERAPEUTICS CORP (US) | 2010-11-10 | — | — | EP | disclosed |
| EP-0893432-B1 | PHENYLETHANOLAMINOTETRALINCARBOXAMIDE DERIVATIVES | KISSEI PHARMACEUTICAL (JP) | 2006-11-08 | — | — | EP | disclosed |
| CN-1100033-C | Phenylthanolaminotetralin carboxamide derivatives | KISSEI PHARMACEUTICAL (JP) | 2003-01-29 | — | — | CN | disclosed |
| US-6046192-A | Phenylethanolaminotetralincarboxamide derivatives | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| CN-1219926-A | Phenethanolamino-1, 2,3, 4-tetrahydronaphthalenyloxyalkyl amide derivatives | KISSEI PHARMACEUTICAL (JP) | 1999-06-16 | — | — | CN | disclosed |
| EP-0893432-A1 | PHENYLETHANOLAMINOTETRALINCARBOXAMIDE DERIVATIVES | Kissei Pharmaceutical Co. Ltd. (JP) | 1999-01-27 | — | — | EP | disclosed |
| US-5691385-A | PHENETHANOLAMINES | ELI LILLY AND COMPANY (US) | 1997-11-25 | — | — | US | disclosed |
| US-5643967-A | ANIMAL GROWTH REGULATORS OF BETA-PHENETHANOLAMINES FOR FEED EFFICIENCY | ELI LILLY AND COMPANY (US) | 1997-07-01 | — | — | US | disclosed |
| US-5631298-A | B-PHENETHANOLAMINES | ELI LILLY AND COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| EP-0204948-B1 | GROWTH PROMOTION OF ANIMALS WITH PHENETHANOL AMINES | ELI LILLY AND COMPANY (US) | 1990-03-28 | — | — | EP | disclosed |
| US-4849453-A | ANIMAL GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1989-07-18 | — | — | US | disclosed |
| EP-0117647-B1 | IMPROVEMENTS IN OR RELATING TO PHENETHANOLAMINES | ELI LILLY AND COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |
| US-4734437-A | PHENETHANOLAMINES | ELI LILLY AND COMPANY (US) | 1988-03-29 | — | — | US | disclosed |
| US-4690951-A | B-PHENETHANGLAMINES; FEED EFFICIENCY AND LEANESS | ELI LILLY AND COMPANY (US) | 1987-09-01 | — | — | US | disclosed |
| EP-0204948-A1 | Growth promotion of animals with phenethanol amines | ELI LILLY AND COMPANY (US) | 1986-12-17 | — | — | EP | disclosed |
| EP-0196849-A2 | Aminohydroxyalkylbenzene anti-obesity and/or anti-hyperglycaemic agents | BEECHAM GROUP PLC (GB) | 1986-10-08 | — | — | EP | disclosed |
| EP-0117647-A1 | Improvements in or relating to phenethanolamines | ELI LILLY AND COMPANY (US) | 1984-09-05 | — | — | EP | disclosed |
| EP-0007205-A1 | Optically active phenethanolamines, their formulations, use and preparation | ELI LILLY AND COMPANY (US) | 1980-01-23 | — | — | EP | disclosed |
| JP-S5470231-A | PREPARATION OF OPTICALLY ACTIVE BENZYL ALCOHOL DERIVATIVE | TANABE SEIYAKU CO LTD | 1979-06-05 | — | — | JP | disclosed |