Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28499778 | 0.99 | HTT (0.42) | HTTCHRM2HTR1AADRA2AADRA2B | |
| SCHEMBL28509027 | 0.91 | MAPT (0.46) | HTTMEN1KMT2ALMNAHPGD | |
| Hydrochloric Acid SCHEMBL28489288 | 0.90 | MAPT (0.45) | HTTMEN1KMT2ALMNAHPGD | |
| SCHEMBL28496363 | 0.90 | HTT (0.34) | HTTCHRM2HTR1AADRA2AADRA2B | |
| SCHEMBL23035174 | 0.86 | NPC1 (0.56) | HTTCHRM2HTR1AADRA2AADRA2B | |
| SCHEMBL23035199 | 0.85 | NPC1 (0.58) | HTTCHRM2HTR1AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL23035301 | 0.85 | NPC1 (0.55) | HTTCHRM2HTR1AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL23035341 | 0.84 | NPC1 (0.57) | HTTCHRM2HTR1AADRA2AADRA2B | |
| SCHEMBL28903652 | 0.83 | EPHX2 (0.35) | EPHX2 | |
| SCHEMBL28494641 | 0.83 | NAMPT (0.35) | HTTCHRM2HTR1AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635963-B | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2020-11-20 | — | — | CN | disclosed |