Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28496363 | 0.93 | HTT (0.34) | EPHX2MAPTNPC1RAB9AHTT | |
| SCHEMBL28488686 | 0.83 | HTT (0.43) | EPHX2MAPTNPY5RNPC1RAB9A | |
| SCHEMBL28487668 | 0.83 | TRPV1 (0.45) | EPHX2TRPV1 | |
| Hydrochloric Acid SCHEMBL28499778 | 0.82 | HTT (0.42) | EPHX2MAPTNPY5RNPC1RAB9A | |
| SCHEMBL28509027 | 0.81 | MAPT (0.46) | MAPTHTTLMNAHPGDTSHR | |
| Hydrochloric Acid SCHEMBL28489288 | 0.80 | MAPT (0.45) | MAPTHTTLMNAHPGDTSHR | |
| SCHEMBL18197780 | 0.80 | NAMPT (0.34) | NAMPTEPHX2MAPTNPC1RAB9A | |
| SCHEMBL28491264 | 0.80 | EPHX2 (0.34) | EPHX2 | |
| SCHEMBL21832067 | 0.79 | L3MBTL1 (0.47) | MAPTLMNASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL28496390 | 0.77 | LMNA (0.39) | NAMPTMAPTNPY5RLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635963-B | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2020-11-20 | — | — | CN | claimed |
| CN-107635963-B | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2020-11-20 | — | — | CN | disclosed |