SCHEMBL28488980

SCHEMBL28488980

CCCC(CC(=O)O)N(C(=O)OCC)C1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ACE P12821 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TSHR P16473 3/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
FFAR1 O14842 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28481799 0.92 TSHR (0.36) ALDH1A1MEN1KMT2ASMN1; SMN2CYP1A2
SCHEMBL21522890 0.89 CYP2D6 (0.39) ALDH1A1MEN1KMT2ASMN1; SMN2CYP1A2
SCHEMBL28489549 0.89 ALDH1A1 (0.35) ALDH1A1MEN1KMT2ASMN1; SMN2CYP1A2
SCHEMBL28481182 0.89 MEN1 (0.37) ALDH1A1MEN1KMT2ASMN1; SMN2TSHR
SCHEMBL28482934 0.82 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ASMN1; SMN2CYP1A2
SCHEMBL21522944 0.82 CYP2D6 (0.37) ALDH1A1MEN1KMT2ASMN1; SMN2CYP1A2
SCHEMBL20166074 0.81 SMN1; SMN2 (0.39) ALDH1A1MEN1KMT2ASMN1; SMN2ACE
SCHEMBL28488446 0.80 TSHR (0.36) ALDH1A1MEN1KMT2ASMN1; SMN2CYP1A2
SCHEMBL28488967 0.80 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ASMN1; SMN2CYP1A2
SCHEMBL28489538 0.80 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109890852-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2020-10-20 CN disclosed