Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950772 | 0.80 | KMT2A (0.61) | KMT2AMEN1MAPTTDP1ALDH1A1 | |
| SCHEMBL2455073 | 0.80 | KMT2A (0.61) | KMT2AMEN1MAPTTDP1ALDH1A1 | |
| SCHEMBL15049401 | 0.80 | KMT2A (0.61) | KMT2AMEN1MAPTTDP1ALDH1A1 | |
| SCHEMBL3972844 | 0.76 | KMT2A (0.50) | KMT2AMEN1MAPTTDP1ALDH1A1 | |
| SCHEMBL12640455 | 0.75 | KMT2A (0.50) | KMT2AMEN1MAPTTDP1ALDH1A1 | |
| SCHEMBL16204244 | 0.75 | KMT2A (0.50) | KMT2AMEN1MAPTTDP1ALDH1A1 | |
| SCHEMBL10338542 | 0.74 | KMT2A (0.48) | KMT2AMEN1MAPTTDP1ALDH1A1 | |
| SCHEMBL8074234 | 0.74 | KMT2A (0.50) | KMT2AMEN1MAPTTDP1ALDH1A1 | |
| SCHEMBL28483326 | 0.72 | HPGD (0.47) | MAPTALDH1A1KDM4EL3MBTL1CES2 | |
| SCHEMBL28578684 | 0.72 | POLB (0.65) | KMT2AMEN1MAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106967151-B | Multi-site combination modified endomorphin analogue and synthesis and application thereof | 兰州大学 | 2020-08-11 | — | — | CN | claimed |