Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950772 | 1.00 | KMT2A (0.61) | KMT2APOLBPTPN1PKMPTPN7 | |
| SCHEMBL15049401 | 1.00 | KMT2A (0.61) | KMT2APOLBPTPN1PKMPTPN7 | |
| SCHEMBL3972844 | 0.83 | KMT2A (0.50) | KMT2APOLBPTPN1PKMPTPN7 | |
| SCHEMBL16204244 | 0.81 | KMT2A (0.50) | KMT2APOLBPTPN1PKMPTPN7 | |
| SCHEMBL10338542 | 0.80 | KMT2A (0.48) | KMT2APOLBPTPN1PKMPTPN7 | |
| SCHEMBL28489015 | 0.80 | KMT2A (0.50) | KMT2APOLBPTPN1PKMPTPN7 | |
| SCHEMBL28578684 | 0.78 | POLB (0.65) | KMT2APOLBPTPN1PKMPTPN7 | |
| SCHEMBL2454068 | 0.78 | KMT2A (0.60) | KMT2APOLBPTPN1PKMPTPN7 | |
| SCHEMBL2454069 | 0.78 | KMT2A (0.60) | KMT2APOLBPTPN1PKMPTPN7 | |
| SCHEMBL335985 | 0.78 | KMT2A (0.60) | KMT2APOLBPTPN1PKMPTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606881-B1 | Cyclic pentapeptides having a beta-turn and a gamma-turn | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-05-12 | — | — | EP | claimed |
| US-5658885-A | OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-19 | — | — | US | claimed |
| US-4043991-A | Preparation of peptides and cephalosporins | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-08-23 | — | — | US | claimed |
| WO-2024018354-A1 | A PROCESS FOR THE SYNTHESIS OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS AND INTERMEDIATES THEREOF | PI INDUSTRIES LTD. (IN) | 2024-01-25 | — | — | WO | disclosed |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-10851119-B2 | Boron-containing diacylhydrazines | INTREXON CORPORATION (US) | 2020-12-01 | — | — | US | disclosed |
| US-10730906-B2 | Multi-step synthesis of templated molecules | NUEVOLUTIONS A/S (DK) | 2020-08-04 | — | — | US | disclosed |
| US-10730906-B2 | Multi-step synthesis of templated molecules | NUEVOLUTIONS A/S (DK) | 2020-08-04 | — | — | US | disclosed |
| US-20200157122-A1 | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORP (US) | 2020-05-21 | — | — | US | disclosed |
| EP-0626174-A2 | Methods and compositions for the prophylactic and/or therapeutic treatment of organ hypofunction | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-11-30 | — | — | EP | disclosed |
| WO-1993025580-A1 | CYCLIC PEPTIDES THAT MODULATE ENDOTHELIN ACTIVITY | IMMUNOPHARMACEUTICS, INC. (US) | 1993-12-23 | — | — | WO | disclosed |
| EP-0436189-B1 | ENDOTHELIN ATAGONISTIC CYCLIC PENTAPEPTIDES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| EP-0436189-A1 | Endothelin atagonistic cyclic pentapeptides | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-07-10 | — | — | EP | disclosed |
| US-4684642-A | BACTERICIDES | PFIZER INC. (US) | 1987-08-04 | — | — | US | disclosed |
| US-4395412-A | 7α-Methoxycephalosporins | TOYAMA CHEMICAL CO., LTD. (JP) | 1983-07-26 | — | — | US | disclosed |
| US-4321265-A | 7α-Methoxycephalosporins | TOYAMA CHEMICAL CO., LTD. (JP) | 1982-03-23 | — | — | US | disclosed |
| US-4061852-A | BACTERICIDE | E. R. SQUIBB & SONS, INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4043991-A | Preparation of peptides and cephalosporins | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10851119-B2 | Boron-containing diacylhydrazines | CD22, BRDT, BCR | KMT2A 1526/4885POLB 4516/4885PTPN1 2224/4885 |
| US-20200157122-A1 | BORON-CONTAINING DIACYLHYDRAZINES | CD22, BRDT, BCR | KMT2A 1526/4885POLB 4516/4885PTPN1 2224/4885 |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | PAICS, LNPEP, DNPEP | KMT2A 1875/4885POLB 3976/4885PTPN1 1154/4885 |
| US-10730906-B2 | Multi-step synthesis of templated molecules | COASY, DAP3, EMG1 | KMT2A 2387/4885POLB 70/4885PTPN1 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.