Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | LSS | P48449 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28497471 | 0.84 | ALDH1A1 (0.59) | ALDH1A1POLBHSD17B10MAPTKMT2A | |
| SCHEMBL28498338 | 0.84 | ALDH1A1 (0.65) | ALDH1A1POLBHSD17B10MAPTKMT2A | |
| SCHEMBL28498694 | 0.82 | CYP19A1 (0.45) | ALDH1A1POLBHSD17B10LSSMAPT | |
| SCHEMBL28498335 | 0.81 | CA1 (0.60) | ALDH1A1POLBHSD17B10MAPTKMT2A | |
| SCHEMBL28509136 | 0.81 | ALDH1A1 (0.56) | ALDH1A1POLBHSD17B10MAPTKMT2A | |
| SCHEMBL28498349 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LSSMAPTLMNASMN1; SMN2 | |
| SCHEMBL13381543 | 0.79 | ALDH1A1 (0.62) | ALDH1A1POLBHSD17B10MAPTKMT2A | |
| SCHEMBL28498697 | 0.76 | KMT2A (0.44) | ALDH1A1CYP19A1KMT2A | |
| SCHEMBL10462588 | 0.76 | LSS (0.67) | ALDH1A1LSSMAPTCYP19A1KMT2A | |
| SCHEMBL4639131 | 0.75 | ALDH1A1 (0.58) | ALDH1A1POLBHSD17B10MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110932-B | Method for synthesizing phthalide tetrahydroisoquinoline compound by tandem cyclization strategy | 沈阳药科大学 | 2021-12-28 | — | — | CN | disclosed |
| CN-112110932-A | Method for synthesizing phthalide tetrahydroisoquinoline compound by tandem cyclization strategy | 沈阳药科大学 | 2020-12-22 | — | — | CN | disclosed |